Want to Improve Your Cholesterol? Don’t Lower It. There’s a Smarter Approach.


“There is a wealth of…evidence that increasing the concentration of HDL cholesterol through diet will lower the risk of coronary artery disease.” –R.P. Mensink, Maastricht University

In the last post we showed how Eating Fat Does Not Hurt Cholesterol & It’s Not About Lowering Cholesterol Anyway. Here’s where the confusion about cholesterol comes from in the first place. There are different types of cholesterol, and most of them are helpful or neutral. The two most commonly discussed are LDL (low-density lipoprotein) and HDL (high-density lipoprotein). They are required to produce new cells and hormones. Because of this critical role, even if we never ate any cholesterol, our liver or intestines would produce it.

What Are Healthy Cholesterol Numbers?

Table of Contents

When it comes to predicting heart health, the American Heart Association, International Diabetes Federation, and World Health Organization agree that low HDL cholesterol—not high LDL cholesterol—is what matters. And that low HDL is bad. Looking at disease and death rates at various levels of LDL and HDL cholesterol, researchers have found that people with low HDL run a much greater risk of heart disease.


Learn the exact foods you must eat if you want to finally lose weight permanently. Click here to download your free Weight Loss Food List, the “Eat More, Lose More” Weight Loss Plan, and the “Slim in 6” Cheat Sheet…CLICK HERE FOR FREE “HOW TO” WEIGHT LOSS GUIDES

Relative Risk of Heart Disease Given Total Cholesterol

(Total Cholesterol in Parenthesis)


There are two things to note about this graphic. First, total cholesterol is irrelevant. If someone tells you their total cholesterol is 185, what is their risk of heart disease? Looking at the preceding table, it is either very low or high, depending on how much of that 185 consists of HDL cholesterol. Similarly, if someone tells you their total cholesterol is 245, they either have a herculean heart or a hemorrhaging heart, depending on their HDL levels.

Second, note how increasing HDL cholesterol is more important for heart health than decreasing LDL cholesterol. High HDL cholesterol protects us from heart problems more than dropping our LDL levels ever could. Heart-healthy diets are not about lowering total cholesterol. They are about raising HDL cholesterol.

“…low HDL-cholesterol levels increase coronary heart disease risk…[programs] resulting in an increase in HDL-cholesterol levels could decrease the incidence of ischemic heart disease.” – J.P. Despres, Laval University


How to Raise HDL Cholesterol

The most effective way to raise our HDL levels is to eat more natural fat and less unnatural starch. Fat raises HDL. Starch lowers HDL.

The Impact of Fat and Starch on HDL and LDL Cholesterol and Health


A Smarter Science of Heart Healthy Foods

Since lower HDL does more harm than lower LDL does good, any diet which tells us to replace SANE sources of fat with inSANE starch worsens our cholesterol. This is why D. Mozaffarian at Harvard University wrote: “[Focusing] on effects of total and saturated fat on…total and low-density lipoprotein [LDL] cholesterol may have failed to reduce coronary heart disease risk and inadvertently worsened…insulin resistance, and weight gain.” Researcher A. Garg wrote the following in the Journal of the American Medical Association: “High-carbohydrate diets…caused persistent deterioration of glycemic control and accentuation of hyperinsulinemia [caused clogs], as well as increased…very-low-density lipoprotein [bad] cholesterol levels.”

Regrettably, under the government’s guidelines, we are supposed to replace natural foods containing fat with low-fat-high-starch products to lower our total cholesterol. Why? Lower total cholesterol is meaningless, and lower HDL cholesterol is terrible for us. Researchers have demonstrated this for decades.

For example, the February 1989 issue of the Diabetes Care journal put out by the American Diabetes Association contained a study comparing the government’s diet with a more SANE way of eating. The study concluded: “VLDL [bad] cholesterol was significantly increased…High-density lipoprotein [good] cholesterol concentrations were significantly decreased after consumption of the 60% carbohydrate diet.”

Comparable results were found with the equally imbalanced U.K. dietary guidelines. In the words of University of Glasgow researcher S.R. Arefhosseini: “Following the U.K. dietary guidelines resulted in changes…more likely to favor an increased risk of coronary heart disease.”


What About Saturated Fat and Cholesterol?

Even saturated fats are not cholesterol criminals. The American Heart Association found:

“No adequately designed randomized controlled study in the general population has shown that…decreasing saturated fat…intake significantly decreases coronary heart disease mortality.”


Bottom Line: Ways to Improve Cholesterol

What is the bottom line? Studies show that any diet telling you to replace SANE sources of fat with inSANE starches is unhealthy and fattening. M.L. McCullough at Harvard University made this point: “Limiting unsaturated fats, which is usually done by increasing carbohydrates…is detrimental…. Low-fat, high-carbohydrate diets provide a higher glycemic load, aggravate hyperinsulinemia [clogging], and may thus increase the risk of diabetes and coronary artery disease.”

Want to improve your cholesterol naturally? Eat more, but smarter.

Sadly, the government’s diet tells us to do exactly what science says we should avoid.

If you think this is troubling, wait until you see what happened when big business jumped on the government bandwagon. We’ll cover that next week.

  1. “Cholesterol : LIPID MAPS–Nature Lipidomics Gateway.” Home : LIPID MAPS–Nature Lipidomics Gateway. N.p., n.d. Web. 3 Jan. 2011. <http://www.lipidmaps.org/update/2009/090501/full/lipidmaps.2009.3.html>.
  2. Apoundert CM, Campos H, Stampfer MJ, et al. Blood levels of long-chain n-3 fatty acids and the risk of sudden death. N Engl J Med 2002;346:1113-1118.
  3. Apoundert CM, Gaziano JM, Willett WC, Manson JE. Nut consumption and decreased risk of sudden cardiac death in the Physicians’ Health Study. Arch Intern Med. 2002;162:1382-1387.
  4. Arefhosseini SR, Edwards CA, Malkova D, Higgins S. Effect of advice to increase carbohydrate and reduce fat intake on dietary profile and plasma lipid concentrations in healthy postmenopausal women. Ann Nutr Metab. 2009;54(2):138-44. Epub 2009 Apr 1. PubMed PMID: 19339775.
  5. Augustin LS, Franceschi S, Jenkins DJ, Kendall CW, La Vecchia C. Glycemic index in chronic disease: a review. Eur J Clin Nutr. 2002 Nov;56(11):1049-71. Review. PubMed PMID: 12428171.
  6. Coulston AM, Hollenbeck CB, Swislocki AL, Reaven GM. Persistence of hypertriglyceridemic effect of low-fat high-carbohydrate diets in NIDDM patients. Diabetes Care. 1989 Feb;12(2):94-101. PubMed PMID: 2539286.
  7. Despres JP. Krauss R. Obesity and Lipoprotein Metabolism In: Bray GA, Couchard d, James WP, eds. Handbook of Obesity. New York: Marcel Dekker, 1997: 651-675.
  8. Gardner CD, Kiazand A, Alhassan S, Kim S, Stafford RS, Balise RR, Kraemer HC, King AC. Comparison of the Atkins, Zone, Ornish, and LEARN diets for change in weight and related risk factors among overweight premenopausal women: The A TO Z Weight Loss Study: a randomized trial. JAMA. 2007 Mar 7;297(9):969-77. Erratum in: JAMA. 2007 Jul 11;298(2):178. PubMed PMID: 17341711.
  9. German JB, Dillard CJ. Saturated fats: what dietary intake? Am J Clin Nutr. 2004 Sep;80(3):550-9. Review. PubMed PMID: 15321792.
  10. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC, Jr, Spertus JA Costa F. Diagnosis and Management of the Metabolic Syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005, 112:2735-2752: originally published online September 12, 2005; doi: 10.1161/CIRCULATIONAHA.105.169404]
  11. Haskell WL, Lee IM, Pate RR, Powell KE, Blair SN, Franklin BA, Macera CA, Heath GW, Thompson PD, Bauman A; American College of Sports Medicine; American Heart Association. Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation. 2007 Aug 28;116(9):1081-93. Epub 2007 Aug 1. PubMed PMID: 17671237.
  12. http://www.idf.org/webdata/docs/IDF_Meta_def_final.pdf
  13. Hu FB, Manson JE, Willett WC. Types of dietary fat and risk of coronary heart disease: a critical review. J Am Coll Nutr. 2001 Feb;20(1):5-19. Review. PubMed PMID: 11293467.
  14. Hu FB, Stampfer MJ, Manson JE, et al. Dietary fat intake and the risk of coronary heart disease in women. N Engl J Med 1997;337:1491–9.
  15. Jump DB, Clarke SD, thelen A, Liimatta M. Coordinate regulation of glycolytic and lipogenic gene expression by polyunsaturated fatty acids. J Lipid Res. 1994 Jun;35(6):1076-84. PubMed PMID: 8077846.
  16. Kersten S. Mechanisms of nutritional and hormonal regulation of lipogenesis. EMBO Rep. 2001 Apr;2(4):282-6. Review. PubMed PMID: 11306547; PubMed Central PMCID: PMC1083868.
  17. Lee-Han H, Cousins M, Beaton M, McGuire V, Kriukov V, Chipman M, Boyd N. Compliance in a randomized clinical trial of dietary fat reduction in patientswith breast dysplasia. Am J Clin Nutr. 1988 Sep;48(3):575-86. PubMed PMID: 3046298.
  18. Lopez-Garcia E, Schulze MB, Manson JE, Meigs JB, Apoundert CM, Rifai N, Willett WC, Hu FB. Consumption of (n-3) fatty acids is related to plasma biomarkers of inflammation and endothelial activation in women. J Nutr. 2004 Jul;134(7):1806-11. PubMed PMID: 15226473.
  19. Marchioli R, Barzi F, Bomba E, et al, GISSI-Prevenzione Investigators. Early protection against sudden dealth by n-3 polyunsaturated fatty acids after myocardial infarction: Time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto Miocardico (GISSI)-Prevenzione. Circulation. 2002;105:1897-1903.
  20. McCullough ML, Feskanich D, Stampfer MJ, Rosner BA, Hu FB, Hunter DJ, Variyam JN, Colditz GA, Willett WC. Adherence to the Dietary Guidelines for Americans and risk of major chronic disease in women. Am J Clin Nutr. 2000 Nov;72(5):1214-22. PubMed PMID: 11063452.
  21. Mensink RP, Katan MB. Effect of monounsaturated fatty acids versus complex carbohydrates on high-density lipoproteins in healthy men and women. Lancet. 1987 Jan 17;1(8525):122-5. PubMed PMID: 2879969.
  22. Mensink RP, Zock PL, Kester AD, Katan MB. Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. Am J Clin Nutr. 2003 May;77(5):1146-55. PubMed PMID: 12716665.
  23. Mensink RP, Zock PL, Kester AD, Katan MB. Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids
  24. Mensink RPM, Katan MB. Effect of dietary trans fatty acids on highdensity and low-density lipoprotein cholesterol levels in healthy subjects. N Engl J Med 1990;323:439–45.
  25. Mori TA, Beilin LJ. Omega-3 fatty acids and inflammation. Curr Atheroscler Rep. 2004 Nov;6(6):461-7. Review. PubMed PMID: 15485592.
  26. Mozaffarian D. Effects of dietary fats versus carbohydrates on coronary heart disease: a review of the evidence. Curr Atheroscler Rep. 2005 Nov;7(6):435-45.Review. PubMed PMID: 16256001     &     Garg A, Bantle JP, Henry RR, Coulston AM, Griver KA, Raatz SK, Brinkley L, Chen YD, Grundy SM, Huet BA, et al. Effects of varying carbohydrate content of diet in patients with non-insulin-dependent diabetes mellitus. JAMA. 1994 May 11;271(18):1421-8. PubMed PMID: 7848401.
  27. Parks EJ, Hellerstein MK. Carbohydrate-induced hypertriacylglycerolemia: historical perspective and review of biological mechanisms. Am J Clin Nutr. 2000 Feb;71(2):412-33. Review. PubMed PMID: 10648253.
  28. Pirozzo S, Summerbell C, Cameron C, Glasziou P. Should we recommend low-fat diets for obesity? Obes Rev. 2003 May;4(2):83-90. Review. Erratum in: Obes Rev. 2003 Aug;4(3):185. PubMed PMID: 12760443.
  29. Ravnskov U. The questionable role of saturated and polyunsaturated fatty acids in cardiovascular disease. J Clin Epidemiol. 1998 Jun;51(6):443-60. Review. PubMed PMID: 9635993.
  30. Sacks FM, Katan M. Randomized clinical trials on the effects of dietary fat and carbohydrate on plasma lipoproteins and cardiovascular disease. Am J Med. 2002 Dec 30;113 Suppl 9B:13S-24S. Review. PubMed PMID: 12566134.
  31. Sands SA, Reid KJ, Windsor SL, Harris WS. The impact of age, body mass index, and seafood intake on the EPA and DHA content of human erythrocytes. Lipids 2005;40:343-347.
  32. Sharman MJ, Kraemer WJ, Love DM, Avery NG, Gómez AL, Scheett TP, Volek JS. A ketogenic diet favorably affects serum biomarkers for cardiovascular disease in normal-weight men. J Nutr. 2002 Jul;132(7):1879-85. PubMed PMID: 12097663.
  33. Simopoulos AP. Essential fatty acids in health and chronic disease. Am J Clin  Nutr. 1999 Sep;70(3 Suppl):560S-569S. Review. PubMed PMID: 10479232.
  34. Simopoulos AP. The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomed Pharmacother. 2002 Oct;56(8):365-79. Review. PubMed PMID: 12442909.
  35. Siscovick DS, Raghunathan TE, King I, Weinmann S, Wicklund KG, Apoundright J, Bovbjerg V, Arbogast P, Smith H, Kushi LH, Cobb LA, Copass MK, Psaty BM, Lemaitre R, Retzlaff B, Childs M, Knopp RH. Dietary intake and cell membrane levels of long-chain n-3 polyunsaturated fatty acids and the risk of primary cardiac arrest. JAMA 1995;274:1363-1367.
  36. Willett W. Challenges for public health nutrition in the 1990s. Am J Public Health. 1990 Nov;80(11):1295-8. PubMed PMID: 2240291; PubMed Central PMCID: PMC1404889.
  37. Willett WC, Stampfer MJ, Manson JE, et al. Intake of trans fatty acids and risk of coronary heart disease among women. Lancet 1993;341:581–5.
  38. Wood, Philip A.. How fat works. Cambridge: Harvard University Press, 2006. Print.
Learn the exact foods you must eat if you want to finally lose weight permanently. Click here to download your free Weight Loss Food List, the “Eat More, Lose More” Weight Loss Plan, and the “Slim in 6” Cheat Sheet…CLICK HERE FOR FREE “HOW TO” WEIGHT LOSS GUIDES
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