Calories Aren’t All That Matter…Ask Anyone Taking Insulin

Starvation Is NOT Healthy. Stop counting calories & go #SANE w/me at http://SANESolution.com

 

“Insulin has profound metabolic effects in the determination of body weight…” – B. Dokken, University of Arizona

The critical effect hormones have on body fat has been well known in scientific circles for a long time. Especially the hormone insulin. Three quick examples:

  • A study in the journal Diabetic Medicine found that giving patients the hormone insulin “is associated with weight gain,” specifically, “an increase in trunk [belly] fat mass.
  • The journal Diabetes and Metabolism reports: “Most studies report an average 13.2 lb. weight gain during the first year following the initiation of insulin therapy.” The journal went on to conclude that when it comes to taking shots of the hormone insulin “weight gain seems mandatory.”
  • In the journal Diabetes an aptly title study “Intensive Insulin Therapy and Weight Gain in IDDM (type 1 diabetes)” revealed that after only two months, “Body weight increased ~6 lbs. with intensive insulin therapy as a result of an increase in fat mass.”
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Note that there’s no mention of “eating too much” or “exercising too little.” That’s because calories aren’t all that matter. Hormones matter a lot. Hundreds of millions of diabetics have proven this for years. And that’s why long-term fat loss and robust health isn’t about eating less of a hormonally-poor traditional diet and doing more hormonally-irrelevant traditional exercise. These techniques may mask our hormonal breakdown, but they do not fix it.

Long-term fat loss and robust health isn’t about eating less of a hormonally-poor traditional diet and doing more hormonally-irrelevant traditional exercise.

Forget counting calories. Focus on eating more hormonally-helpful SANE foods, and doing less, but hormonally-helpful eccentric exercise. Eat more and exercising less–smarter. Sure that seems like the opposite of what we’ve been told to do, but isn’t it about time to get the opposite of what we’ve gotten?


  1. Carlson MG & Campbell PJ. Intensive insulin therapy and weight gain in IDDM. Diabetes 1993 42 1700–1707.
  2. Laville M, Andreelli F. [Mechanisms for weight gain during blood glucose normalization]. Diabetes Metab. 2000 Jun;26 Suppl 3:42-5. Review. French. PubMed PMID: 10945152.
  3. From Research to Practice/The Art and Science of Obesity Management: Betsy B. Dokken and Tsu-Shuen Tsao the Physiology of Body Weight Regulation: Are We Too Efficient for Our Own Good? Diabetes Spectrum July 2007 20:166-170; doi:10.2337/diaspect.20.3.166
  4. Sinha A, Formica C, Tsalamandris C, Panagiotopoulos S, Hendrich E, DeLuise M, Seeman E, Jerums G. Effects of insulin on body composition in patients with insulin-dependent and non-insulin-dependent diabetes. Diabet Med. 1996 Jan;13(1):40-6. PubMed PMID: 8741811.
Learn the exact foods you must eat if you want to finally lose weight permanently. Click here to download your free Weight Loss Food List, the “Eat More, Lose More” Weight Loss Plan, and the “Slim in 6” Cheat Sheet…CLICK HERE FOR FREE “HOW TO” WEIGHT LOSS GUIDES

Studies Show It’s InSANE To Claim “A Calorie Is A Calorie”

Starvation Is NOT Healthy. Stop counting calories & go #SANE w/me at http://SANESolution.com

A few posts ago we covered the four factors that prove a calorie isn’t a calorie when it comes to how much they help us burn fat and boost our health:Satiety, Aggression, Nutrition, and Efficiency.  Satiety is how quickly calories fill us up. Aggression is how likely calories are to be stored as body fat. Nutrition is how many vitamins, minerals, amino acids, essential fatty acids, etc., calories provide. Efficiency is how easily calories are converted into body fat. Whether a calorie is high-quality or low-quality depends on where it fits on the SANEity spectrum.

High-quality calories are on the healthy end of the SANEity spectrum. They are Satisfying, unAggressive, Nutritious, and inEfficient. They fill us up quickly and keep us full for a long time. They provide a lot of nutrients, and few of them can be converted into body fat. Even better, they trigger the release of body-fat-burning hormones, clear clogs, and lower our set-point. In short, they are SANE.

Learn the exact foods you must eat if you want to finally lose weight permanently. Click here to download your free Weight Loss Food List, the “Eat More, Lose More” Weight Loss Plan, and the “Slim in 6” Cheat Sheet…CLICK HERE FOR FREE “HOW TO” WEIGHT LOSS GUIDES

Low-quality calories are just the opposite. They are on the unhealthy end of the SANEity spectrum. They are unSatisfying, Aggressive, non-Nutritious, and Efficient. They trigger the release of body-fat-storing hormones, cause clogs, and raise our set-point. In short, they are inSANE.

Why does this matter?

In all of the studies that follow, everyone ate the exact same quantityof calories, but one group’s calories were of much higher quality (were much more SANE) than the other groups’:

  • University of Florida researcher J.W. Krieger analyzed eighty-seven studies and found that those people who ate SANEcalories lost an average of twelve more pounds of body fat compared to those who ate an equal quantity of inSANEcalories.
  • C.M. Young at Cornell University split people into three groups, each eating 1,800 calories per day, but at different levels of SANEity. The most SANE group lost 86.5% more body fat than the least SANEgroup.
  • In the Annals of Internal Medicine, F.L. Benoît compared a reduced-calorie inSANE diet to a reduced-calorieSANE diet. After ten days the SANE diet burned twice as much body fat.
  • Additional studies by researchers U. Rabast (1978,1981), P. Greene (2003), N.H. Baba (1999), A. Golay (1996), M.E. Lean (1997), C.M. Young (1971), and D.K. Layman (2003) all show that people who ate SANEcalorieslost an average of 22% more weight than those who ate the exact same quantity of inSANEcalories.

In next week’s posts, we’ll begin looking at each of the four factors of SANE eating, starting with Satiety. By the way, if the word seems oddly familiar, it comes from the same root as satisfying.


  1. Baba NH, Sawaya S, Torbay N, Habbal Z, Azar S, Hashim SA: High protein vs high carbohydrate hypoenergetic diet for the treatment of obese hyperinsulinemic subjects. Int J Obes Relat Metab Disord 1999, 23:1202-6.
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  4. Golay A, Allaz AF, Morel Y, de Tonnac N, Tankova S, Reaven G: Similar weight loss with low- or high-carbohydrate diets. Am J Clin Nutr 1996, 63:174-8.
  5. Golay A, Eigenheer C, Morel Y, Kujawski P, Lehmann T, de Tonnac N: Weight-loss with low or high carbohydrate diet? Int J Obes Relat Metab Disord 1996, 20:1067-72.
  6. Greene P, Willett W, Devecis J, Skaf A: Pilot 12-Week Feeding Weight-Loss Comparison: Low-Fat vs Low-Carbohydrate (Ketogenic) Diets. Obesity Research 2003, 11:A23.
  7. Krieger JW, Sitren HS, Daniels MJ, Langkamp-Henken B. Effects of variation in protein and carbohydrate intake on body mass and composition during energy restriction: a meta-regression 1. Am J Clin Nutr. 2006 Feb;83(2):260-74. PubMed PMID: 16469983.
  8. Layman DK, Boileau RA, Erickson DJ, Painter JE, Shiue H, Sather C, Christou DD: A reduced ratio of dietary carbohydrate to protein improves body composition and blood lipid profiles during weight loss in adult women. J Nutr 2003, 133:411-7.
  9. Lean ME, Han TS, Prvan T, Richmond PR, Avenell A: Weight loss with high and low carbohydrate 1200 kcal diets in free living women. Eur J Clin Nutr 1997, 51:243-8.
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  11. Rabast U, Hahn A, Reiners C, Ehl M: Thyroid hormone changes in obese subjects during fasting and a very-low-calorie diet. Int J Obes 1981, 5:305-11.
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Learn the exact foods you must eat if you want to finally lose weight permanently. Click here to download your free Weight Loss Food List, the “Eat More, Lose More” Weight Loss Plan, and the “Slim in 6” Cheat Sheet…CLICK HERE FOR FREE “HOW TO” WEIGHT LOSS GUIDES

Is obesity a disease? My 2 cents…would love to hear yours.

Starvation Is NOT Healthy. Stop counting calories & go #SANE w/me at http://SANESolution.com

Recently recorded a wonderful bonus podcast with the lovely Carole Carson (http://www.fromfat2fit.com) who asked for my two cents on the recent debate about calling obesity a disease. Given the timeliness of this, wanted to share the clip now, and be sure to stay tuned for the delightful entire show with Carole in the coming months.


Learn the exact foods you must eat if you want to finally lose weight permanently. Click here to download your free Weight Loss Food List, the “Eat More, Lose More” Weight Loss Plan, and the “Slim in 6” Cheat Sheet…CLICK HERE FOR FREE “HOW TO” WEIGHT LOSS GUIDES

ObesityADisease

Q&A: What about alcohol?

Starvation Is NOT Healthy. Stop counting calories & go #SANE w/me at http://SANESolution.com

Calories provided by the vast majority of alcoholic beverages are inSANE. That doesn’t mean we must avoid all alcoholic beverages. It means that given our goal of minimizing inSANE calories, the best alcoholic beverages are those with the least calories.

Learn the exact foods you must eat if you want to finally lose weight permanently. Click here to download your free Weight Loss Food List, the “Eat More, Lose More” Weight Loss Plan, and the “Slim in 6” Cheat Sheet…CLICK HERE FOR FREE “HOW TO” WEIGHT LOSS GUIDES

Calorie Quality Factor 2: Aggression (The “A” in SANE)

Starvation Is NOT Healthy. Stop counting calories & go #SANE w/me at http://SANESolution.com

“The crucial factor is not how much is eaten…or how much is expended, but how…those calories are utilized and made available when needed.” – Gary Taubes, in Good Calories, Bad Calories

A calorie is not a calorie when it comes to how likely it is to be stored as body fat. We can think about human biology like this: When we eat, a traffic cop tells calories where to go. How Aggressively calories approach this traffic cop determines their chances of being stored as body fat.

The traffic cop directs calories to repair, fuel, or fatten us—in that order. It first makes sure we have enough fuel to rebuild anything that has broken down. Next, it keeps us doing whatever we are doing. Last, it seeks to protect us from starving. As long as we have a calm and consistent flow of calories coming into our system, the cop does a great job directing them.

Learn the exact foods you must eat if you want to finally lose weight permanently. Click here to download your free Weight Loss Food List, the “Eat More, Lose More” Weight Loss Plan, and the “Slim in 6” Cheat Sheet…CLICK HERE FOR FREE “HOW TO” WEIGHT LOSS GUIDES

However, when calories approach the traffic cop Aggressively, it gets angry, throws its clipboard down, and sends those calories to fat cells. Our body is fine with a lot of food. It is Aggressive food that aggravates it. Five hundred calm calories creeping into the bloodstream over many hours are less likely to be stored as body fat than five hundred Aggressive calories rushing in all at once. Like the rest of us, our body does not do its best work when dealing with a bunch of Aggressive requests all at once.

To best understand calories’ Aggression we first need to understand how our body fuels itself. It does not run on the food we eat. It runs primarily on glucose, a sugar our body creates from the food we eat. That may seem like a meaningless distinction, but it is not.

Storing body fat is not caused by eating a lot of food. Storing body fat is about a response to eating food that causes us to have more glucose in our bloodstream than we can use at one time. That is why calories’ Aggression matters so much. The more Aggressive calories are, the faster they increase the levels of glucose in our bloodstream. The faster calories increase our glucose levels, the more likely we are to have more glucose than the body can deal with at one time. That’s when it shuttles the excess into our fat cells.

The distinction between “a lot of food” and “a lot of glucose right now” is important. We can eat all the food we want and never gain body fat if the glucose the food generates does not exceed the glucose level we can deal with right then. Fortunately, SANE foods prevent excess glucose from getting into our bloodstream. If we simply focus on increasing the amount of water-, fiber-, and protein-packed high-Satiety foods we are eating, we will automatically avoid Aggressive calories and store less body fat.


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  20. van Amelsvoort JM, Weststrate JA. (1992). Amylose-amylopectin ratio in a meal affects postprandial variables in male volunteers. Am. J. Clin. Nutr., 55: 712-718.
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Learn the exact foods you must eat if you want to finally lose weight permanently. Click here to download your free Weight Loss Food List, the “Eat More, Lose More” Weight Loss Plan, and the “Slim in 6” Cheat Sheet…CLICK HERE FOR FREE “HOW TO” WEIGHT LOSS GUIDES

Calorie Quality Factor 3: Nutrition Part 1 (The “N” in SANE)

Starvation Is NOT Healthy. Stop counting calories & go #SANE w/me at http://SANESolution.com

“Low energy density [high Nutrition] is not an inevitable characteristic of low-fat diets; as many of the low-fat foods presently being promoted in our commercial food supply are based on sugar or highly refined carbohydrates.” – W.C. Willett, Harvard University

Two hundred and fifty calories of Twinkies are not the same as 250 calories of broccoli. Clearly a calorie is not a calorie when we are discussing the Nutrition we need to burn body fat and be healthy. So what is nutritious? Like everything else, the key to Nutrition is quality, but all we are ever told about is quantity—aka the Nutrition facts labels on food.

The information found on food labels tells us half of what determines Nutrition: the quantity of nutrients in the food. The other half is the quality of the calories we are getting along with those nutrients.

Learn the exact foods you must eat if you want to finally lose weight permanently. Click here to download your free Weight Loss Food List, the “Eat More, Lose More” Weight Loss Plan, and the “Slim in 6” Cheat Sheet…CLICK HERE FOR FREE “HOW TO” WEIGHT LOSS GUIDES

Talking merely about the quantity of nutrients in food leads to a very fattening view of Nutrition. Consider the American Heart Association’s endorsement logos on boxes of sugar-stuffed cereal because the cereal was “enriched.” A high quantity of nutrients combined with low-quality calories is not nutritious.

Most people already know that thinking about the quantity of nutrients in food is not sufficient. We know that ten doughnuts are not ten times as nutritious as one doughnut. We have to consider nutrients relative to calories, or Nutrition quality.

Determining Nutrition quality is simple. We take the nutrient quantity information provided on Nutrition labels and divide it by the number of calories in a serving of the food. This provides the food’s Nutrition per calorie. Many nutrients per calorie—provided by non-starchy vegetables, seafood, lean meats, select dairy, and fruits—means high Nutrition. Few nutrients per calorie—see starches and sweets—means low Nutrition.

For example, here’s how one cup of enriched wheat flour compares to one cup of spinach in terms of nutrient quantity. I’ve shaded the cell of the food with more of the given nutrient when we measure by the cup.

 

Looking at quantity, enriched wheat flour seems more nutritious than spinach. Here’s why that’s misleading:

One cup of enriched wheat flour contains 495 calories. One cup of spinach contains 7 calories.

Looking at quality—nutrients per calorie—we see something much different—and more useful.

 

 

When we make a fair comparison—comparing 250 calories of enriched wheat flour against 250 calories of spinach, instead of comparing 495 calories of enriched wheat flour against 7 calories of spinach—we see that spinach is dramatically more nutritious than enriched wheat flour.

Looking at Nutrition this way is useful for two reasons we’ll cover in the next post.


  1. Willett WC. Is dietary fat a major determinant of body fat? Am J Clin Nutr. 1998 Mar;67(3 Suppl):556S-562S. Review. Erratum in: Am J Clin Nutr 1999 Aug;70(2):304. PubMed PMID: 9497170.
  2. Nestle, Marion. What to Eat. 1 ed. New York: North Point Press, 2007. Print.
  3. USDA SR-21
Learn the exact foods you must eat if you want to finally lose weight permanently. Click here to download your free Weight Loss Food List, the “Eat More, Lose More” Weight Loss Plan, and the “Slim in 6” Cheat Sheet…CLICK HERE FOR FREE “HOW TO” WEIGHT LOSS GUIDES